{"title":"Methylation, B Vitamins \u0026 Folate","description":"\u003cp\u003eMethylfolate, methylcobalamin, P5P and B-complex formulas for methylation and homocysteine support. Selected by Dr. Lorn Allison, DN; ships direct from the maker.\u003c\/p\u003e","products":[{"product_id":"p5p-50-activated-b6","title":"Pure Encapsulations P5P 50 (Activated Vitamin B6) 50 mg — 60 \/ 180 Capsules","description":"\u003cdiv id=\"description-ac\" class=\"content active\" style=\"display: block;\"\u003e\n\u003cul\u003e\n\u003cli\u003eThe main form of plasma B6*\u003c\/li\u003e\n\u003cli\u003eHelps metabolize carbohydrates, fats and proteins*\u003c\/li\u003e\n\u003cli\u003eMade with hypoallergenic, vegan ingredients\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eP5P 50 is the predominant form of plasma B6 and provides a wide range of physiological support. 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This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":40409619726391,"sku":"NI51","price":58.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1951\/2795\/files\/niacitol-reg-no-flush-niacin-500-mg-120-s-ni51.jpeg.mst_1.webp?v=1701473326"},{"product_id":"b6-complex","title":"Pure Encapsulations B6 Complex — 60 \/ 120 Capsules","description":"\u003cp\u003e\u003cstrong\u003eActivated B Complex with the B6 Turned Up\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eMost B complexes give you a flat, even dose across the board. 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Thorne's purity testing. Also available in 5 mg for high-dose repletion.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eProtocol fit:\u003c\/strong\u003e pairs with methyl-B12 and Magnesium Glycinate in methylation protocols; Thorne Basic B is the multi-B partner. Pure Encapsulations Folate 1,000 is the equivalent 1 mg dose as Metafolin.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFAQ — 1 mg or 5 mg?\u003c\/strong\u003e 1 mg is the everyday maintenance dose; 5 mg is for practitioner-directed repletion or high homocysteine.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFAQ — Can methylfolate make me anxious?\u003c\/strong\u003e A small number of people feel wired at higher doses — start at 1 mg and take it in the morning.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSupplement Facts:\u003c\/strong\u003e Serving size 1 capsule, 60 servings. Folate (as L-5-Methyltetrahydrofolate) 1.7 mg DFE (1 mg). 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This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Thorne","offers":[{"title":"Default Title","offer_id":42432685080631,"sku":"B129","price":24.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1951\/2795\/files\/b129__v9e2dcbdfca9045f29cc531eca894e0722dd58f27.png?v=1788740352"},{"product_id":"thorne-5-mthf-5-mg","title":"Thorne 5-MTHF 5 mg — High-Dose Methylfolate, 60 Capsules","description":"\u003cp\u003e\u003cstrong\u003eThorne 5-MTHF 5 mg — repletion-strength active folate\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThis is the same L-5-methyltetrahydrofolate as Thorne's 1 mg capsule at five times the dose, for the situations where maintenance folate isn't enough: stubborn homocysteine, documented folate deficiency, or a protocol your practitioner has set at the higher level.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWho I reach for it with:\u003c\/strong\u003e elevated homocysteine that hasn't responded to 1 mg; homozygous MTHFR variants under supervision; mood protocols where the literature used 5–15 mg; folate repletion on labs.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWhat makes it different:\u003c\/strong\u003e 8,500 mcg DFE in a clean capsule — no folic acid, no fillers beyond cellulose and leucine. Thorne's testing.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eProtocol fit:\u003c\/strong\u003e run it with methyl-B12 — high-dose folate without B12 can mask a B12 deficiency. Step down to the 1 mg capsule once labs normalize.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFAQ — Do I need a practitioner for this dose?\u003c\/strong\u003e Yes — 5 mg is a therapeutic dose. Use it as directed and retest homocysteine in 8–12 weeks.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFAQ — Any side effects?\u003c\/strong\u003e Restlessness or irritability in sensitive people; take it in the morning and reduce if needed.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSupplement Facts:\u003c\/strong\u003e Serving size 1 capsule, 60 servings. Folate (as L-5-Methyltetrahydrofolate) 8.3 mg DFE (5 mg). 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This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Thorne","offers":[{"title":"Default Title","offer_id":42432685113399,"sku":"B132","price":68.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1951\/2795\/files\/b132__vb756dcd0935201b31dcbf32c4d4a9df6c46a822c.png?v=1788740367"},{"product_id":"pure-encapsulations-folate-1000","title":"Pure Encapsulations Folate 1,000 — Metafolin L-5-MTHF 1,000 mcg, 90 Capsules","description":"\u003cp\u003e\u003cstrong\u003ePure Encapsulations Folate 1,000 — Metafolin, the original active folate\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eMetafolin is the Merck-patented L-5-MTHF that most of the early methylfolate research was done with. Pure Encapsulations delivers 1,000 mcg of it per capsule with nothing but cellulose and a vegetarian capsule around it — a folate that works regardless of MTHFR genetics.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWho I reach for it with:\u003c\/strong\u003e MTHFR variants; methylation, neurotransmitter and DNA-synthesis support; cardiovascular and homocysteine protocols; pre-conception; anyone who wants the most hypoallergenic folate available.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWhat makes it different:\u003c\/strong\u003e Metafolin form, 90 capsules, and Pure Encapsulations' free-from standard — no wheat, gluten, soy, dairy, coatings or magnesium stearate.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eProtocol fit:\u003c\/strong\u003e pairs with methyl-B12 and Magnesium Glycinate; Thorne 5-MTHF and Designs for Health L-5-MTHF are the same 1 mg dose in other forms and counts.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFAQ — Is this the same as 5-MTHF?\u003c\/strong\u003e Yes — Metafolin is L-5-methyltetrahydrofolate, the same active molecule.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFAQ — When should I take it?\u003c\/strong\u003e One capsule daily with a meal.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSupplement Facts:\u003c\/strong\u003e Serving size 1 capsule, 90 servings. Folate (as Metafolin, L-5-MTHF) 1,667 mcg DFE (1,000 mcg L-5-MTHF). Other ingredients: hypoallergenic plant fiber (cellulose), vegetarian capsule (cellulose, water).\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSuggested Use:\u003c\/strong\u003e As a dietary supplement, take 1 capsule daily, with a meal, or as directed by your healthcare professional.\u003c\/p\u003e\u003cp\u003eFlat $11.99 shipping, free over $250.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eSelected by Dr. Lorn Allison, DN.\u003c\/em\u003e\u003c\/p\u003e\u003cp\u003e\u003cem\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":42432685506615,"sku":"FOL19","price":34.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1951\/2795\/files\/pe-folate-1000-front.jpg?v=1788741210"},{"product_id":"thorne-vitamin-b12-methylcobalamin-1-mg","title":"Thorne Vitamin B12 1 mg — Methylcobalamin, 60 Capsules","description":"\u003cp\u003e\u003cstrong\u003eThorne Vitamin B12 1 mg — the standard methyl-B12 dose in a clean capsule\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eOne capsule gives you 1,000 mcg (1 mg) of methylcobalamin, the active, tissue-ready form of vitamin B12 that the body uses directly in its methylation pathways. 1,000 mcg is the dose I start most people on because it adjusts so easily: one capsule a day for maintenance, two a day for 2,000 mcg, up to three if your practitioner directs it.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWho I reach for it with:\u003c\/strong\u003e vegetarians and vegans; adults over 50 and anyone with low stomach acid or on acid-blocking medication, since those groups absorb B12 from food poorly; people on metformin; fatigue and brain-fog workups; methylation and homocysteine protocols alongside active folate.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWhat makes it different:\u003c\/strong\u003e nothing in the capsule but methylcobalamin, a cellulose capsule, leucine, microcrystalline cellulose and silicon dioxide. Free from gluten, dairy and soy, and third-party tested by Thorne for purity and label accuracy.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eProtocol fit:\u003c\/strong\u003e pairs with Thorne 5-MTHF 1 mg for methylation support. Prefer a liquid you can dose by the drop? Apex Vitamin B12 (K34) and B12-Max (K56). Prefer a larger bottle? Pure Encapsulations Methylcobalamin comes in 180 capsules. Designs for Health Vitamin B12 is a 5,000 mcg lozenge.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFAQ — Why methylcobalamin instead of cyanocobalamin?\u003c\/strong\u003e Methylcobalamin is already in the active form the body uses, so there's no conversion step. It's the form I recommend.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFAQ — Capsule, liquid or lozenge?\u003c\/strong\u003e Once you're taking methylcobalamin at the right amount, B12 products are fairly interchangeable. Choose the form you'll actually take every day.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSupplement Facts:\u003c\/strong\u003e Serving size 1 capsule, 60 servings. Vitamin B12 (as methylcobalamin) 1 mg. Other ingredients: hypromellose (derived from cellulose) capsule, leucine, microcrystalline cellulose, silicon dioxide.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSuggested Use:\u003c\/strong\u003e Take 1 capsule one to three times daily or as recommended by your health-care practitioner.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWarnings:\u003c\/strong\u003e Contraindicated in anyone with a history of hypersensitivity to any of its ingredients. If pregnant, consult your health-care practitioner before using this product.\u003c\/p\u003e\u003cp\u003eFlat $11.99 shipping, free over $250.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eSelected by Dr. Lorn Allison, DN.\u003c\/em\u003e\u003c\/p\u003e\u003cp\u003e\u003cem\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Thorne","offers":[{"title":"Default Title","offer_id":42438816727095,"sku":"B125","price":24.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1951\/2795\/files\/b125__vdc2295bdfd7f57713849ab8693465dc3ee2e45a0.png?v=1789156084"},{"product_id":"apex-energetics-vitamin-b12-k34-liquid","title":"Apex Energetics Vitamin B12 (K34) — Liquid Methylcobalamin 500 mcg, 118 Servings","description":"\u003cp\u003e\u003cstrong\u003eApex Energetics Vitamin B12 (K34) — liquid methyl-B12 you dose by the drop\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eMost B12 comes in fixed 1,000 or 5,000 mcg pills. This is a liquid: 500 mcg of methylcobalamin in every 10 drops (0.25 mL). That makes it one of the simplest ways to hit an exact daily amount — 20 drops for 1,000 mcg, 40 drops for 2,000 mcg — and to step the dose up or down later without buying a different product.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWho I reach for it with:\u003c\/strong\u003e people who don't want to swallow capsules; patients I expect to adjust on B12 over time; vegetarians and vegans; adults with low stomach acid, who absorb B12 from food poorly; energy and methylation protocols.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWhat makes it different:\u003c\/strong\u003e methylcobalamin, the biologically active form of B12, dissolved in a glycerin base with natural tangerine flavor and stevia — no capsule, fillers or excipients. Vegetarian formula, tested for gluten and dairy. 118 servings per bottle.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eProtocol fit:\u003c\/strong\u003e B12-Max (K56) is the same liquid at 1,250 mcg per 10 drops for higher daily amounts. For a capsule, Thorne Vitamin B12 and Pure Encapsulations Methylcobalamin are 1,000 mcg each; Designs for Health Vitamin B12 is a 5,000 mcg lozenge. Super Methyl-SP covers broader methylation support.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFAQ — How many drops is 1,000 mcg?\u003c\/strong\u003e About 20 drops (0.5 mL). 1,000 mcg is the standard starting dose because it's easy to build on; follow your practitioner's direction.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFAQ — K34 or B12-Max?\u003c\/strong\u003e Same formula, different strength. K34 suits everyday and fine-tuned dosing; B12-Max gets you to higher amounts in fewer drops.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSupplement Facts:\u003c\/strong\u003e Serving size 0.25 mL (approx. 10 drops), 118 servings. Vitamin B12 (as methylcobalamin) 500 mcg. Other ingredients: glycerin, alcohol, natural tangerine flavor, stevia extract.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSuggested Use:\u003c\/strong\u003e Take 0.25 mL (approx. 10 drops) orally 3 times a day, or as directed by your healthcare professional.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWarning:\u003c\/strong\u003e Consult your healthcare professional before use if pregnant, nursing, taking medications, or for any use by minors. Do not use if safety seal is broken or missing. Keep out of reach of children. Store at room temperature away from direct sunlight and keep the bottle tightly closed.\u003c\/p\u003e\u003cp\u003eFlat $11.99 shipping, free over $250.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eSelected by Dr. Lorn Allison, DN.\u003c\/em\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eShips direct from Apex Energetics\u003c\/strong\u003e — never third-party or gray-market stock. Apex sells only through licensed practitioners, so every bottle leaves their facility the week it is ordered.\u003c\/p\u003e\u003cp\u003e\u003cem\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Apex Energetics","offers":[{"title":"Default Title","offer_id":42438818725943,"sku":"K34","price":20.98,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1951\/2795\/files\/0003884_vitamin-b12.png?v=1789156131"},{"product_id":"apex-energetics-b12-max-k56-liquid","title":"Apex Energetics B12-Max™ (K56) — Liquid Methylcobalamin 1,250 mcg, 118 Servings","description":"\u003cp\u003e\u003cstrong\u003eApex Energetics B12-Max (K56) — high-potency liquid methyl-B12\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eB12-Max is the stronger version of Apex's liquid B12: 1,250 mcg of methylcobalamin in every 10 drops (0.25 mL). It's for higher daily amounts in fewer drops, while keeping what I like about a liquid — you can set the dose exactly. About 16 drops gives 2,000 mcg; 10 drops gives 1,250 mcg.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWho I reach for it with:\u003c\/strong\u003e practitioner-directed higher-dose B12; people with a history of low B12 who need more than a maintenance dose; those who don't want to swallow pills; vegetarians and vegans; energy, nerve and methylation protocols.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWhat makes it different:\u003c\/strong\u003e methylcobalamin, the biologically active form of B12, dissolved in a glycerin base with natural tangerine flavor and stevia — no capsule, fillers or excipients. Vegetarian formula, tested for gluten and dairy. 118 servings per bottle.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eProtocol fit:\u003c\/strong\u003e Vitamin B12 (K34) is the same liquid at 500 mcg per 10 drops for everyday or fine-tuned dosing. For a 1,000 mcg capsule, see Thorne Vitamin B12 or Pure Encapsulations Methylcobalamin; Designs for Health Vitamin B12 is a 5,000 mcg lozenge.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFAQ — Do I need the Max strength?\u003c\/strong\u003e Most people start around 1,000 mcg, which is the standard dose because it adjusts upward easily. B12-Max makes sense when your practitioner wants you higher than that.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFAQ — Liquid, capsule or lozenge?\u003c\/strong\u003e Once you're using methylcobalamin at the right amount, the form mostly comes down to how you like to take it. A liquid wins when the dose needs to be precise.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSupplement Facts:\u003c\/strong\u003e Serving size 0.25 mL (approx. 10 drops), 118 servings. Vitamin B12 (as methylcobalamin) 1,250 mcg. Other ingredients: glycerin, alcohol, natural tangerine flavor, stevia extract.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSuggested Use:\u003c\/strong\u003e Take 0.25 mL (approx. 10 drops) orally 3 times a day, or as directed by your healthcare professional.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWarning:\u003c\/strong\u003e Consult your healthcare professional before use if pregnant, nursing, taking medications, or for any use by minors. Do not use if safety seal is broken or missing. Keep out of reach of children. Store at room temperature away from direct sunlight and keep the bottle tightly closed.\u003c\/p\u003e\u003cp\u003eFlat $11.99 shipping, free over $250.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eSelected by Dr. Lorn Allison, DN.\u003c\/em\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eShips direct from Apex Energetics\u003c\/strong\u003e — never third-party or gray-market stock. Apex sells only through licensed practitioners, so every bottle leaves their facility the week it is ordered.\u003c\/p\u003e\u003cp\u003e\u003cem\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Apex Energetics","offers":[{"title":"Default Title","offer_id":42438818758711,"sku":"K56","price":27.98,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1951\/2795\/files\/0003291_b12-max.png?v=1789156149"},{"product_id":"pure-encapsulations-methylcobalamin-1000-mcg","title":"Pure Encapsulations Methylcobalamin 1,000 mcg — Vitamin B12 Capsules, 60 or 180 Count","description":"\u003cp\u003e\u003cstrong\u003ePure Encapsulations Methylcobalamin 1,000 mcg — hypoallergenic methyl-B12, in the bottle size that fits you\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eEach capsule holds 1,000 mcg of methylcobalamin, the active, methylated form of vitamin B12, with nothing around it but plant cellulose and a vegetarian capsule. 1,000 mcg is the standard starting dose because it builds so easily: one capsule for maintenance, two for 2,000 mcg, up to three daily as your practitioner directs. The 180-count bottle is the better value for anyone taking more than one a day.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWho I reach for it with:\u003c\/strong\u003e sensitive patients who react to fillers and additives; vegetarians and vegans; adults with low stomach acid or on acid-blocking medication, who absorb B12 from food poorly; fatigue, nerve and cognitive support; methylation and homocysteine protocols.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWhat makes it different:\u003c\/strong\u003e Pure Encapsulations' free-from standard — no wheat, gluten, soy, dairy, eggs, tree nuts, peanuts, artificial colors or sweeteners, coatings, magnesium stearate or unnecessary binders and fillers. Methylcobalamin has a natural red color, so capsule contents can range from off-white to lightly pink.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eProtocol fit:\u003c\/strong\u003e pairs with Pure Encapsulations Folate 1,000 for methylation support. Thorne Vitamin B12 is the same 1,000 mcg dose in a 60-count bottle; Apex Vitamin B12 (K34) and B12-Max (K56) are liquids you can dose by the drop; Designs for Health Vitamin B12 is a 5,000 mcg lozenge.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFAQ — 60 or 180 capsules?\u003c\/strong\u003e At one a day, 60 lasts two months. At two a day (2,000 mcg), the 180-count lasts three months and costs less per capsule.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFAQ — Does the form matter more than the brand?\u003c\/strong\u003e Once you're taking methylcobalamin at the right amount, B12 products are fairly interchangeable. Capsule, liquid or lozenge mostly comes down to how you prefer to take it.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSupplement Facts:\u003c\/strong\u003e Serving size 1 capsule, 60 or 180 servings. Vitamin B12 (as methylcobalamin) 1,000 mcg. Other ingredients: hypoallergenic plant fiber (cellulose), vegetarian capsule (cellulose, water).\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSuggested Use:\u003c\/strong\u003e As a dietary supplement, take 1 capsule, 1–3 times daily, with meals. For ages 18 and up.\u003c\/p\u003e\u003cp\u003eFlat $11.99 shipping, free over $250.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eSelected by Dr. Lorn Allison, DN.\u003c\/em\u003e\u003c\/p\u003e\u003cp\u003e\u003cem\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"60 Capsules","offer_id":42438818791479,"sku":"MT6","price":20.5,"currency_code":"USD","in_stock":true},{"title":"180 Capsules","offer_id":42438818824247,"sku":"MT1","price":49.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1951\/2795\/files\/pure-encapsulations-methylcobalamin-mt6-front.jpg?v=1789156274"},{"product_id":"apex-methyl-sp-k14","title":"Apex Energetics Methyl-SP™ (K14) — Methylation \u0026 Homocysteine Support with Folinate, B12 \u0026 TMG, 90 Capsules","description":"\u003ch2\u003eMethylation Support for People Who Overreact to Methylfolate\u003c\/h2\u003e\u003cp\u003eSome patients feel wired, anxious, or headachy on high-dose methylfolate. For them I want the methylation pathway supported with folinic acid instead, which the body converts at its own pace. Methyl-SP is Apex's folinate version: 1,200 mcg DFE of calcium folinate, 600 mcg methylcobalamin, active B6 and B2, 550 mg trimethylglycine, MSM, beet root, and vitamins C and E. Apex designs it to support liver methylation and the transsulfuration of homocysteine.*\u003c\/p\u003e\u003ch3\u003eWho I Reach For This With\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eHomocysteine running high on a lab\u003c\/li\u003e\n\u003cli\u003eMTHFR variants in someone who didn't tolerate methylfolate\u003c\/li\u003e\n\u003cli\u003eFatigue, fog, or mood symptoms with low B12 or folate\u003c\/li\u003e\n\u003cli\u003eAs the methylation piece under a detox program\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eWhat Makes This Form Different\u003c\/h3\u003e\u003cp\u003eApex makes two. \u003cstrong\u003eMethyl-SP\u003c\/strong\u003e (this one) uses folinate at 1,200 mcg. \u003cstrong\u003e\u003ca href=\"\/products\/super-methyl-sp\"\u003eSuper Methyl-SP\u003c\/a\u003e\u003c\/strong\u003e steps the folate up to 2,500 mcg. Start with Methyl-SP unless your practitioner wants the higher dose; TMG at 550 mg per serving is the same in both.\u003c\/p\u003e\u003ch3\u003eHow It Fits Into a Protocol\u003c\/h3\u003e\u003cp\u003eTwo capsules two to three times a day with food, 90 days, homocysteine before and after. Runs alongside \u003ca href=\"\/products\/apex-metacrin-dx-k10\"\u003eMetacrin-DX\u003c\/a\u003e during liver work.\u003c\/p\u003e\u003ch3\u003eFrequently Asked Questions\u003c\/h3\u003e\u003cp\u003e\u003cstrong\u003eFolinate or methylfolate?\u003c\/strong\u003e\u003cbr\u003eFolinate is one step back in the pathway and gentler for people who overreact. If you do fine on methylfolate, either works.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCan I take it with a B-complex?\u003c\/strong\u003e\u003cbr\u003eWatch the totals; this is already a high-potency B6, B2, and B12 source.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWhy the 60-day note?\u003c\/strong\u003e\u003cbr\u003eApex recommends using it within 60 days of opening to keep the B vitamins at full potency.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSuggested Use:\u003c\/strong\u003e Take 2 capsules 2 to 3 times a day, or as directed by your healthcare professional. 90 vegetarian capsules per bottle.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eSelected by Dr. Lorn Allison, DN.\u003c\/em\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eShips direct from Apex Energetics\u003c\/strong\u003e — never third-party or gray-market stock. Apex sells only through licensed practitioners, so every bottle leaves their facility the week it is ordered.\u003c\/p\u003e\u003cp\u003e\u003cem\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Apex Energetics","offers":[{"title":"Default Title","offer_id":67590513655863,"sku":"K14","price":37.98,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1951\/2795\/files\/0004134_methyl-sp_353.png?v=1790986595"},{"product_id":"apex-super-b-zyme-z24","title":"Apex Energetics Super B-Zyme™ (Z24) — High-Potency B-Complex with Methylfolate, Methyl B12 \u0026 Enzymes, 90 Capsules","description":"\u003ch2\u003eThe B-Complex for the Person Who Burns Through B Vitamins\u003c\/h2\u003e\u003cp\u003eStress, alcohol, sugar, and most medications all pull on the B vitamins, and the first sign is usually energy and mood going flat together. Super B-Zyme is Apex's high-potency complex: all eight B vitamins at serious doses, with folate as methylfolate, B12 as methylcobalamin, B6 in both forms, plus choline, inositol, PABA, and the Zyme-line enzyme blend. Apex notes the sources are selected and prepared to maximize vitality and nutritional value.*\u003c\/p\u003e\u003ch3\u003eWho I Reach For This With\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eFatigue with a high-stress, high-caffeine lifestyle\u003c\/li\u003e\n\u003cli\u003eAnyone on a medication known to deplete B vitamins (ask your pharmacist which)\u003c\/li\u003e\n\u003cli\u003eVegetarians and vegans for the B12\u003c\/li\u003e\n\u003cli\u003eAs the B-vitamin base under a methylation or energy protocol\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eWhat Makes This Form Different\u003c\/h3\u003e\u003cp\u003eMethylated forms and an enzyme blend set it apart from a drugstore B-complex. \u003ca href=\"\/products\/apex-methyl-sp-k14\"\u003eMethyl-SP\u003c\/a\u003e is the targeted methylation formula with TMG; Super B-Zyme is the broad daily complex. If you take both, mind the B6 total.\u003c\/p\u003e\u003ch3\u003eHow It Fits Into a Protocol\u003c\/h3\u003e\u003cp\u003eOne to two capsules twice a day with meals. With \u003ca href=\"\/products\/apex-adreno-zyme-z05\"\u003eAdreno-Zyme\u003c\/a\u003e when the adrenals are the story.\u003c\/p\u003e\u003ch3\u003eFrequently Asked Questions\u003c\/h3\u003e\u003cp\u003e\u003cstrong\u003eWill my urine turn bright yellow?\u003c\/strong\u003e\u003cbr\u003eYes; that's riboflavin and it's harmless.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eIs 147 mg of B6 safe?\u003c\/strong\u003e\u003cbr\u003eApex's two-capsule serving is high-potency. Take the lower dose unless your practitioner directs otherwise, and don't stack it with other high-B6 products long term.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCan I take it at night?\u003c\/strong\u003e\u003cbr\u003eB vitamins are energizing for some. Mornings and midday are better.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSuggested Use:\u003c\/strong\u003e Take 1 to 2 capsules 2 times a day with a meal, or as directed by your healthcare professional. 90 vegetarian capsules per bottle.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eSelected by Dr. Lorn Allison, DN.\u003c\/em\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eShips direct from Apex Energetics\u003c\/strong\u003e — never third-party or gray-market stock. Apex sells only through licensed practitioners, so every bottle leaves their facility the week it is ordered.\u003c\/p\u003e\u003cp\u003e\u003cem\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Apex Energetics","offers":[{"title":"Default Title","offer_id":67590515392567,"sku":"Z24","price":35.98,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1951\/2795\/files\/0003179_super-b-zyme_353.png?v=1790987196"},{"product_id":"apex-super-b12-k128","title":"Apex Energetics Super B12™ (K128) — Liposomal Methylcobalamin 1,500 mcg Drops, Raspberry, 112 Servings","description":"\u003ch2\u003eApex's Strongest B12, Made Like Trizomal\u003c\/h2\u003e\u003cp\u003eApex makes three liquid B12s and this is the top one. Super B12 delivers 1,500 mcg of methylcobalamin per 10 drops, prepared with the same liposomal process Apex uses for \u003ca href=\"\/products\/apex-trizomal-glutathione-k122\"\u003eTrizomal Glutathione\u003c\/a\u003e, raspberry flavored, 112 servings per bottle. Apex notes B12 is needed for energy production, neurological function, methylation and DNA synthesis, homocysteine metabolism, red blood cell formation, and endocrine and immune function.*\u003c\/p\u003e\u003ch3\u003eWho I Reach For This With\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eLow or low-normal B12 on a lab\u003c\/li\u003e\n\u003cli\u003eVegans and long-term acid-blocker users\u003c\/li\u003e\n\u003cli\u003eFatigue and numbness-tingling where B12 is the suspect\u003c\/li\u003e\n\u003cli\u003eAnyone who didn't absorb capsule B12 well\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eWhat Makes This Form Different\u003c\/h3\u003e\u003cp\u003eThe three: \u003ca href=\"\/products\/apex-energetics-vitamin-b12-k34-liquid\"\u003eVitamin B12\u003c\/a\u003e at 500 mcg, \u003ca href=\"\/products\/apex-energetics-b12-max-k56-liquid\"\u003eB12-Max\u003c\/a\u003e at 1,250 mcg, and \u003cstrong\u003eSuper B12\u003c\/strong\u003e at 1,500 mcg liposomal. If absorption is the problem, the liposomal one is the answer.\u003c\/p\u003e\u003ch3\u003eHow It Fits Into a Protocol\u003c\/h3\u003e\u003cp\u003eTen drops once a day. With \u003ca href=\"\/products\/apex-methyl-sp-k14\"\u003eMethyl-SP\u003c\/a\u003e when homocysteine is high, or \u003ca href=\"\/products\/apex-super-b-zyme-z24\"\u003eSuper B-Zyme\u003c\/a\u003e for the rest of the B family.\u003c\/p\u003e\u003ch3\u003eFrequently Asked Questions\u003c\/h3\u003e\u003cp\u003e\u003cstrong\u003eUnder the tongue or swallowed?\u003c\/strong\u003e\u003cbr\u003eEither; the liposomal form doesn't depend on sublingual absorption.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCan I take too much B12?\u003c\/strong\u003e\u003cbr\u003eIt's water-soluble and the excess is excreted. Still, use the directed dose.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWhich of the three should I buy?\u003c\/strong\u003e\u003cbr\u003eSuper B12 if you've tested low or absorb poorly. Vitamin B12 (500 mcg) for maintenance.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSuggested Use:\u003c\/strong\u003e Take 0.263 mL (about 10 drops) once a day, or as directed by your healthcare professional. 112 servings per bottle.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eSelected by Dr. Lorn Allison, DN.\u003c\/em\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eShips direct from Apex Energetics\u003c\/strong\u003e — never third-party or gray-market stock. Apex sells only through licensed practitioners, so every bottle leaves their facility the week it is ordered.\u003c\/p\u003e\u003cp\u003e\u003cem\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"Apex Energetics","offers":[{"title":"Default Title","offer_id":67590518407223,"sku":"K128","price":31.98,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1951\/2795\/files\/0003616_super-b12_353.png?v=1790987396"}],"url":"https:\/\/masterthebody.com\/collections\/methylation-b-vitamins-folate.oembed","provider":"Master The Body ","version":"1.0","type":"link"}