Pregnenolone 25 mg — the Upstream Hormone Precursor
Pregnenolone sits at the top of the steroid-hormone cascade — the raw material the body converts into DHEA, progesterone, cortisol, and downstream sex hormones. Production declines steadily with age, and because it's upstream of everything, that decline echoes through the whole hormonal system. It's also studied for its own roles in memory and cognitive function.
Who I reach for it with: age-related hormonal decline patterns under practitioner management; memory and cognitive-support protocols — pregnenolone is active in brain tissue directly; adrenal-recovery cases where the precursor pool is depleted.
What makes it different: Douglas Laboratories' dissolvable tablet format and GMP manufacturing — hormone precursors are a category where sourcing discipline matters more than most, and Douglas has run practitioner-grade for decades. 25 mg is a measured, titratable dose.
Protocol fit: Sits upstream of adrenal support (Adrenal Cortex, Adaptocrine) — some protocols use precursor and glandular together. Hormone-precursor work belongs under practitioner supervision with baseline labs.
FAQ — Is this a hormone? It's the precursor the body makes hormones from — which is exactly why practitioner oversight and lab work matter.
FAQ — Who shouldn't take it? Anyone with hormone-sensitive conditions, without their provider's explicit involvement.
Suggested Use: Take as directed by your healthcare professional. 60 tablets per bottle.
Selected by Dr. Lorn Allison, DN.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.