Pure Encapsulations Methylcobalamin 1,000 mcg — hypoallergenic methyl-B12, in the bottle size that fits you
Each capsule holds 1,000 mcg of methylcobalamin, the active, methylated form of vitamin B12, with nothing around it but plant cellulose and a vegetarian capsule. 1,000 mcg is the standard starting dose because it builds so easily: one capsule for maintenance, two for 2,000 mcg, up to three daily as your practitioner directs. The 180-count bottle is the better value for anyone taking more than one a day.
Who I reach for it with: sensitive patients who react to fillers and additives; vegetarians and vegans; adults with low stomach acid or on acid-blocking medication, who absorb B12 from food poorly; fatigue, nerve and cognitive support; methylation and homocysteine protocols.
What makes it different: Pure Encapsulations' free-from standard — no wheat, gluten, soy, dairy, eggs, tree nuts, peanuts, artificial colors or sweeteners, coatings, magnesium stearate or unnecessary binders and fillers. Methylcobalamin has a natural red color, so capsule contents can range from off-white to lightly pink.
Protocol fit: pairs with Pure Encapsulations Folate 1,000 for methylation support. Thorne Vitamin B12 is the same 1,000 mcg dose in a 60-count bottle; Apex Vitamin B12 (K34) and B12-Max (K56) are liquids you can dose by the drop; Designs for Health Vitamin B12 is a 5,000 mcg lozenge.
FAQ — 60 or 180 capsules? At one a day, 60 lasts two months. At two a day (2,000 mcg), the 180-count lasts three months and costs less per capsule.
FAQ — Does the form matter more than the brand? Once you're taking methylcobalamin at the right amount, B12 products are fairly interchangeable. Capsule, liquid or lozenge mostly comes down to how you prefer to take it.
Supplement Facts: Serving size 1 capsule, 60 or 180 servings. Vitamin B12 (as methylcobalamin) 1,000 mcg. Other ingredients: hypoallergenic plant fiber (cellulose), vegetarian capsule (cellulose, water).
Suggested Use: As a dietary supplement, take 1 capsule, 1–3 times daily, with meals. For ages 18 and up.
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Selected by Dr. Lorn Allison, DN.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.