Pregnenolone 25 mg — the Upstream Hormone Precursor
Pregnenolone sits at the top of the steroid-hormone family tree, and the body makes less of it as the years go by. Douglas puts it this way: "Pregnenolone is often referred to as the grandparent precursor to steroid hormones in mammals,"* and notes that production at age 75 is about 60% lower than at age 35.*
Who I Reach For This With
- Adults who want hormone support built on baseline labs and practitioner guidance
- Patients in age-related hormone discussions where the precursor is part of the conversation
- Protocols that also include adrenal support, where I want the precursor and the adrenal piece planned together
- Anyone who wants a flexible dose: the tablet is bisected, so half or a whole tablet is easy
What Makes This Form Different
- 25 mg of pregnenolone per bisected tablet, so a half tablet gives a lower step
- Douglas: "highest purity pregnenolone" made "under strict Good Manufacturing Practices (GMP) standards"*
- A dissolvable tablet: the label says to let it dissolve in the mouth and then swallow
What Douglas Laboratories Says It Supports*
- "Hormone support"*
- Pregnenolone as "the grandparent precursor to steroid hormones in mammals"*
- Support for brain, nervous tissue, liver, pancreas, reproductive tissues, pituitary and skin function*
How It Fits Into a Protocol
Hormone-precursor work belongs under practitioner supervision with baseline labs. Pregnenolone sits upstream of adrenal support, so some protocols pair it with Adrenal Cortex or Adaptocrine and others do not. We decide that from your labs and how you are doing, not from a standing recipe.
Frequently Asked Questions
Is this a hormone?
It is the precursor the body makes other hormones from, which is why practitioner oversight and lab work matter.
Who should check with their provider first?
Everyone. The label says to consult your physician before using this product. Anyone with a hormone-related health history, or who takes prescription medication, should check with their prescribing provider before adding this.
How do I take it?
The label says adults take 1/2 to 1 tablet daily as directed by your healthcare professional only. Let the tablet dissolve in your mouth, then swallow.
Supplement Facts: Serving size: 1 bisected tablet. Servings per container: 60. Pregnenolone: 25 mg. Other ingredients: cellulose, mannitol, stearic acid, vegetable stearate and silica. Contains no yeast, wheat, gluten, soy, dairy, corn, sodium, sugar, starch or artificial additives.
Suggested Use: Adults take 1/2 to 1 tablet daily as directed by your healthcare professional only. Allow tablet to dissolve in mouth and then swallow. 60 tablets per bottle.
Warnings: NOT FOR USE BY INDIVIDUALS UNDER THE AGE OF 18 YEARS. DO NOT USE IF PREGNANT OR NURSING. Consult your physician before using this product. Do not exceed the recommended serving.
Ships direct from Douglas Laboratories — never third-party or gray-market stock. Every bottle comes straight from their facility, so lot numbers and expiration dates are exactly what Douglas shipped.
Selected by Dr. Lorn Allison, DN.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
