Thorne Vitamin B12 1 mg — the standard methyl-B12 dose in a clean capsule
One capsule gives you 1,000 mcg (1 mg) of methylcobalamin, the active form of vitamin B12. It's the dose I start most people on because it adjusts so easily: one capsule a day, two for 2,000 mcg, up to three if your practitioner directs. Thorne describes it as an "active form of vitamin B12 that supports heart and nerve health, normal circadian rhythms, and healthy methylation."*
Who I Reach For This With
- Vegetarians and vegans
- Adults over 50
- People whose labs show low B12
- Methylation protocols alongside active folate
What Makes This Form Different
- Nothing in the capsule but 1 mg of methylcobalamin, plus leucine, cellulose and silicon dioxide
- Thorne: an "active form of vitamin B12"*
- Gluten free, dairy free and soy free
What Thorne Says It Supports*
- Heart and nerve health*
- Normal circadian rhythms*
- Healthy methylation*
How It Fits Into a Protocol
This pairs with Thorne 5-MTHF 1 mg for methylation support. Prefer a liquid you can dose by the drop? Apex Vitamin B12 (K34) and B12-Max (K56) are options. Prefer a larger bottle? Pure Encapsulations Methylcobalamin comes in 180 capsules.
Frequently Asked Questions
Why methylcobalamin instead of cyanocobalamin?
Methylcobalamin is already in the active form, so there's no conversion step. It's the form I recommend.
Capsule or liquid?
Once you're taking methylcobalamin at the right amount, the forms are fairly interchangeable. Choose the one you'll actually take every day.
How many should I take?
Thorne's label says one to three capsules a day. I usually start with one, and we adjust together.
Supplement Facts: Serving size 1 capsule, 60 servings per container. Vitamin B12 (as Methylcobalamin) 1 mg. Other ingredients: leucine, microcrystalline cellulose, silicon dioxide, hypromellose (derived from cellulose) capsule.
Suggested Use: Take 1 capsule one to three times daily or as recommended by your health-care practitioner. 60 capsules per bottle.
Warnings: Contraindicated in anyone with a history of hypersensitivity to any of its ingredients. If pregnant, consult your health-care practitioner before using this product.
Ships direct from Thorne's own facility — never third-party or gray-market stock. Lot numbers and expiration dates are exactly what Thorne shipped.
Selected by Dr. Lorn Allison, DN.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.