Deglycyrrhizinated Licorice (DGL) is widely recognized for its role in gut repair due to its ability to support and enhance the health of the gastrointestinal mucosa. Here's how DGL may be able to help with gut repair:
DGL stimulates mucus production, which protects the stomach lining and aids in healing ulcers by creating a protective barrier against stomach acid and irritants.
It promotes the regeneration of mucosal cells, increasing the number of mucus-secreting cells in the stomach1.
DGL reduces inflammation by inhibiting inflammatory mediators such as prostaglandins and cytokines (e.g., IL-1β, IL-6).
This anti-inflammatory action helps soothe irritation in the gut lining, especially in conditions like inflammatory bowel disease (IBD) or ulcers.
Instead of suppressing stomach acid like conventional medications, DGL boosts the body's natural defenses by increasing blood flow to damaged tissues and stimulating prostaglandin synthesis, which promotes tissue repair.
DGL has shown activity against Helicobacter pylori, a bacterium linked to ulcers and gastritis, by inhibiting its protein synthesis and DNA replication.
It relaxes the intestinal wall, reducing spasms and aiding in digestive comfort, which can further support gut healing.
Unlike traditional licorice, DGL removes glycyrrhizin to prevent side effects like high blood pressure or potassium imbalance, making it a safer option for long-term use.
In summary, DGL helps with gut repair by promoting mucus production, reducing inflammation, supporting tissue regeneration, and offering antimicrobial benefits—all while being safe for extended use.
Dr. Lorn Allison, DN is a board-certified Doctor of Naprapathic Medicine with over 20 years of clinical experience in digestive health, musculoskeletal medicine, and integrative wellness. He is the founder of Master The Body, a family-owned wellness practice and supplement store in Joliet, Illinois. Learn more about Dr. Allison.
