Glycine — the Quiet Amino Acid Behind Sleep Depth and Detox
Glycine is the smallest amino acid and one of the busiest: an inhibitory neurotransmitter that calms the nervous system, a required ingredient in the liver's phase-two detox conjugation, a building block of collagen, and — in research — a sleep-depth supporter that lowers core body temperature the way natural sleep onset does.
Who I reach for it with: light, unrefreshing sleep — asleep but never deep; pre-bed racing minds needing a gentle downshift; detox protocols where phase-two conjugation needs raw material; joint and connective-tissue support alongside collagen work.
What makes it different: Glycine is unusually well tolerated — sweet-tasting, gentle, and useful at flexible doses — which makes it one of the easiest sleep tools to actually try. Thorne's version carries their purity testing.
Protocol fit: Stacks naturally with Magnesium Glycinate for the sleep-depth combination (and yes — that product already delivers some glycine by design). In liver work it complements Hepato-Synergy on the conjugation side.
FAQ — When for sleep? 30–60 minutes before bed is where the research points.
FAQ — Can I combine it with magnesium? Yes — they're one of the most natural pairings in the sleep toolkit.
Suggested Use: Take as directed by your healthcare professional.
Selected by Dr. Lorn Allison, DN.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.